The HIGH- DEMAND Amino Acids

The high-demand amino acids identified in the InnovAAte research form the building blocks of InnovAAte products

The HIGH-DEMAND Amino Acids

Amino acids are best known as the components used by the body to build proteins. However, the high-demand Amino Acids are lost in copious quantities in sweat and urine and are involved with a large range of important body functions.

The following is a list of examples of key metabolic roles of the six amino acids taken from scientific publications. The objective is to allow you to see the range of vital metabolic functions that these amino acids are involved with - in addition to building proteins. You can access the the original science source here.

  • His

    Histidine

    An essential amino acid

    • Required for synthesis of haemoglobin
      • A deficit in diet can lead to anaemia
    • Required for the formation of carnosine.
      • Carnosine is highly concentrated in the muscles and brain
        • Has many roles including acting as an anti-oxidant
      • Required for the formation of histamine and the immune response
      • Stimulates digestion
      • Histidine is a major component in muscle proteins
  • Ser

    Serine

    Utilised in numerous major pathways of metabolism

    • Sleep
    • Production of DNA
      • Vital for folate metabolism
    • Has a prominent role in cell growth and repair
    • Needed for making cell membranes
    • Precursor for synthesis of numerous metabolites in the body

    Lost in high quantities via sweat

    It can be synthesised by the body, but when demand is high during high-intensity exercise

    • Serine synthesis can be insufficient to meet body demands.
  • Lys

    Lysine

    Is an essential amino acid

    • Required for synthesis of proteins
    • Muscle proteins
    • Soft tissues (collagen)
    • Essential for formation and repair of soft tissues in the body
    • Precursor for the synthesis of carnitine
      • Facilitates mitochondrial oxidation for energy production
    • Lysine enhances the intestinal uptake and conservation of Ca2+

    Lost in high quantities via sweat

  • Asp

    Aspartic acid

    Utilised in numerous major pathways of metabolism

    • The urea cycle for the safe removal of waste nitrogen as urea
    • Energy metabolism
    • Synthesis of DNA
    • Neurotransmitter

     Lost in high quantities via sweat

    Maybe conditionally essential during recovery from injury and infection

  • Gly

    Glycine

    Utilised in numerous major pathways of metabolism

    • Required for collagen synthesis
      • One third of collagen consists of glycine
    • Present in the natural moisturising factor generated in the skin
    • Needed for producing the components of DNA
    • Precursor for synthesis of key metabolites in the body
      • glutathione, creatine

    Lost in high quantities via sweat

    It can be synthesised by the body, but when demand is high during high-intensity exercise

    • Serine synthesis can be insufficient to meet body demands.
  • Orn

    Ornithine

    This amino acid is not used in the synthesis of proteins, but has numerous functions in metabolism

    • Centrally involved in urea metabolism
      • Helps remove waste nitrogen and prevents toxic impact of excess nitrogen
    • Is a precursor for the body to generate arginine
      • Provides an important source of nitric oxide
    • Increases the efficiency of energy consumption
    • Can assist with appetite suppression

    Lost in high quantities via sweat

    Maybe conditionally essential during recovery from injury and infection

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