The HIGH- DEMAND Amino Acids

The high-demand amino acids identified in the InnovAAte research form the building blocks of InnovAAte products

The HIGH-DEMAND Amino Acids

Amino acids are best known as the components used by the body to build proteins. The high-demand Amino Acids, which InnovAAte have identified as being lost in copious quantities in sweat and urine, underpin the integrity of an additional range of important functions in the body.

  • His

    Histidine

    An essential amino acid

    • Required for synthesis of haemoglobin
      • A deficit in diet can lead to anaemia
    • Required for the formation of carnosine.
      • Carnosine is highly concentrated in the muscles and brain
        • Has many roles including acting as an anti-oxidant
      • Required for the formation of histamine and the immune response
      • Stimulates digestion
      • Histidine is a major component in muscle proteins
  • Ser

    Serine

    Utilised in numerous major pathways of metabolism

    • Production of DNA
    • Has a prominent role in cell growth and repair
    • Needed for making cell membranes
    • Precursor for synthesis of numerous metabolites in the body

    Lost in high quantities via sweat

    It can be synthesised by the body, but when demand is high during high-intensity exercise

    • Serine synthesis can be insufficient to meet body demands.
  • Lys

    Lysine

    Is an essential amino acid

    • Required for synthesis of proteins
    • Muscle proteins
    • Soft tissues (collagen)
    • Essential for formation and repair of soft tissues in the body
    • Precursor for the synthesis of carnitine
      • Facilitates mitochondrial oxidation for energy production
    • Lysine enhances the intestinal uptake and conservation of Ca2+

    Lost in high quantities via sweat

  • Asp

    Aspartic acid

    Utilised in numerous major pathways of metabolism

    • The urea cycle for the safe removal of waste nitrogen as urea
    • Energy metabolism
    • Synthesis of DNA
    • Neurotransmitter

     Lost in high quantities via sweat

    Maybe conditionally essential during recovery from injury and infection

  • Gly

    Glycine

    Utilised in numerous major pathways of metabolism

    • Required for collagen synthesis
      • One third of collagen consists of glycine
    • Present in the natural moisturising factor generated in the skin
    • Needed for producing the components of DNA
    • Precursor for synthesis of key metabolites in the body
      • glutathione, creatine

    Lost in high quantities via sweat

    It can be synthesised by the body, but when demand is high during high-intensity exercise

    • Serine synthesis can be insufficient to meet body demands.
  • Orn

    Ornithine

    This amino acid is not used in the synthesis of proteins, but has numerous functions in metabolism

    • Centrally involved in urea metabolism
      • Helps remove waste nitrogen and prevents toxic impact of excess nitrogen
    • Is a precursor for the body to generate arginine
      • Provides an important source of nitric oxide
    • Increases the efficiency of energy consumption
    • Can assist with appetite suppression

    Lost in high quantities via sweat

    Maybe conditionally essential during recovery from injury and infection

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